Prequel Barrier Therapy Skin Protectant Cream - 10 fl oz
$17.99See 1 deal for this item
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$5 Target GiftCard with $30 hair & skin care purchase
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- $17.99($9.00/fluid ounce)$5 Target GiftCard with $30 hair & skin care purchase4.4 out of 5 stars with 184 ratings
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- $6.99$5 Target GiftCard with $30 hair & skin care purchase+ 1 deal3.8 out of 5 stars with 21 ratings
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- $24.99($7.39/fluid ounce)$5 Target GiftCard with $30 hair & skin care purchase4.3 out of 5 stars with 2158 ratings
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- $19.99$5 Target GiftCard with $30 hair & skin care purchase4.5 out of 5 stars with 37 ratings
- $24.99($14.70/fluid ounce)$5 Target GiftCard with $30 hair & skin care purchase4.3 out of 5 stars with 418 ratings
- $17.99 - $19.99$5 Target GiftCard with $30 hair & skin care purchase4.2 out of 5 stars with 824 ratings
- $24.99($14.70/fluid ounce)$5 Target GiftCard with $30 hair & skin care purchase4.4 out of 5 stars with 409 ratings
Frequently bought together
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- $17.99($1.33/fluid ounce)$5 Target GiftCard with $30 hair & skin care purchase4.4 out of 5 stars with 1546 ratings
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Related Categories
3.9 out of 5 stars with 46 reviews
effectiveness: 3.75 out of 5
quality: 3.8 out of 5
value: 3.75 out of 5
66% would recommend
21 recommendations
2 out of 5 stars
30 April, 2026
(no review title)
Love that it's Non greasy but not for sensitive skin I only apply to the top of my hand and it burns my skin.
1 out of 5 stars
Thumbs down graphic, would not recommend
23 April, 2026Verified purchase
Made my skin worse
Absolutely not. I do not recommend this for anyone with sensitive skin. Do not use if you have eczema. This made my skin flare up even worse. Also gave me small bumps all over my arms. I will be returning it.
5 out of 5 stars
Thumbs up graphic, would recommend
23 April, 2026Verified purchase
Try it!
My skin loves this cream, my bank doesn’t though lol … it’s light but still effective without leaving a residue feeling and like the slight oatmeal smell. Good if you have eczema.
5 out of 5 stars
Thumbs up graphic, would recommend
19 April, 2026Verified purchase
Soothing and effective
Amazing formula! Not too heavy and very soothing for my eczema prone family. We all use it! This is a holy grail for us.
5 out of 5 stars
25 March, 2026Verified purchase
(no review title)
My favorite face and body moisturizer.
3 out of 5 stars
24 March, 2026Verified purchase
(no review title)
It did the job with keeping moisture and calming my skin especially with my angry eczema, but i started to form red spots all over my face 🥲
5 out of 5 stars
Thumbs up graphic, would recommend
22 March, 2026Verified purchase
(no review title)
Just tried for a few days and this has stopped my eczema itchiness! My skin loves this! Smell is very subtle too. Thank you! Love!!
2 out of 5 stars
Thumbs down graphic, would not recommend
19 March, 2026Verified purchase
Might just be me
I think I’m one of the few people that found this cream irritating. At first I didn’t notice it but the more I’ve used it the more my skin does not like it. On my body it does okay but it leaves a slight burning feeling on my face compared to other similar creams (ex CerAve, Aveeno, Uriage). I tend to really go for products that cater to barrier protection especially for winter and was so excited to try it but 2 months out and I think it’s just not for me. Please spot test this before using!
5 out of 5 stars
Thumbs up graphic, would recommend
14 March, 2026Verified purchase
GOLD
This lotion does it all. It’s phenomenal as a face and body moisturizer, and I’m saying that as someone with acne prone skin. I don’t quite get the negative reviews. My experience has been amazing!
2 out of 5 stars
7 March, 2026Verified purchase
Good as a body lotion but...
I have very sensitive skin on my face and this made my skin turn very red and itchy. It works well for my body, just not my face, unfortunately.
5 out of 5 stars
Thumbs up graphic, would recommend
27 February, 2026
Buy it!
Phenomenal! Not greasy and hydrates like no other lotion. I’ve been using it for my hands and love it!
1 out of 5 stars
24 February, 2026Verified purchase
Not for Eczema prone skin
Did not help my daughter’s skin with eczema.
1 out of 5 stars
Thumbs down graphic, would not recommend
23 February, 2026Verified purchase
Just beware!
I bought this thinking it will work because I seen so many ads that this was great for Eczema prone skin! So I bought 2 for my older daughter who had this skin problem since she was little but has been maintaining it with making sure she puts her anti itch creams and moisturizing lotions on her. But once she put this on her face it stared to become hot and itchy she she had to rinse it off right away!! And the 2 one was for my youngest son who also has Eczema but wasn't severe as his sister's. But has used it twice and he started to have a itchy rash all over his body!!! And I started to have a rash on my hands and itchy body when I don't even have eczema smh!!!! Had to throw both away!!! I think it was the colloidal oatmeal ingredient that was effecting this rash! Because the other lotions and creams we have been using doesn't have this ingredient in them! So just beware if you have a allergic reaction to oatmeal don't get this!!
3 out of 5 stars
20 February, 2026Verified purchase
(no review title)
Don’t use this on your face/areas that are acne prone. This has a lot of comedogenic ingredients that will clog your pores and cause acne over time. The product is fine but there’s better out there but for a higher price. You get a good price per ounce with this product.
2 out of 5 stars
Thumbs down graphic, would not recommend
17 February, 2026Verified purchase
(no review title)
Be careful using it on your face - I don't have sensitive skin and it made me break out on my forehead with small red acne and made my face feel tight, felt like it didn't help with face barrier repair and clogged the face instead. I've been using it on my body and it's been fine, but it's not too moisturizing because of the thin consistency. Definitely a skip.
5 out of 5 stars
17 February, 2026Verified purchase
(no review title)
incredible moisturizer. dermatologist owned brand. quantity makes it easy to slather everywhere. TYSM
1 out of 5 stars
Thumbs down graphic, would not recommend
16 February, 2026Verified purchase
(no review title)
This did not work for my child with eczema.
5 out of 5 stars
Thumbs up graphic, would recommend
14 February, 2026Verified purchase
Great for Wind-Chapped Skin
I love Prequel, but I especially love this moisturizer. I use it on my face and body, and I feel like it’s perfect for both cases. The fact that it has ceramides and colloidal oatmeal makes it a really good fit for my dry, sensitive, and Midwest-winter wind-chapped face.
5 out of 5 stars
Thumbs up graphic, would recommend
8 February, 2026Verified purchase
GREAT BUY
Highly recommend this cream. Great value and superb ingredients. Cant ask for more. I wish Target had the full Prequel line!
5 out of 5 stars
Thumbs up graphic, would recommend
7 February, 2026
perfect for barista hands
If you're a barista and are struggling with dry hands from the sanitizer, I highly recommend this! It lasts through multiple hand washes.