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Prequel Barrier Therapy Skin Protectant Cream - 10 fl oz: Moisturizing, Ceramides, For Sensitive & Dry Skin, Unscented - 2 of 4Prequel Barrier Therapy Skin Protectant Cream - 10 fl oz: Moisturizing, Ceramides, For Sensitive & Dry Skin, Unscented - 3 of 4Prequel Barrier Therapy Skin Protectant Cream - 10 fl oz: Moisturizing, Ceramides, For Sensitive & Dry Skin, Unscented - 4 of 4
Prequel Barrier Therapy Skin Protectant Cream - 10 fl oz: Moisturizing, Ceramides, For Sensitive & Dry Skin, Unscented - 1 of 4

Prequel Barrier Therapy Skin Protectant Cream - 10 fl oz: Moisturizing, Ceramides, For Sensitive & Dry Skin, Unscented

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At a glance

About this item

Highlights

  • Temporarily alleviates itchiness and minor irritation due to dry skin and eczema
  • Soothes dry, distressed skin
  • Clinically tested 24 hour moisture
  • Non-Greasy
  • Fragrance-Free
  • Steroid-Free
  • Hypoallergenic
  • Allergy-Tested
  • Suitable for All Skin Types
  • Safe for Sensitive Skin
  • Safe for Eczema Prone Skin
  • Dermatologist-Developed
  • Dermatologist-Tested

Description

A skin protectant cream for the face and body that alleviates minor irritation and itchiness due to dryness and eczema flare-ups. Formulated with a potent blend of colloidal oatmeal, multi-ceramide blend, allantoin and adenosine, this soothing cream absorbs easily and provides relief to dry, distressed skin.

To Use: Apply the barrier cream as needed from head to toe.
Scent: Unscented
Health Facts: Contains Ceramides
Product Form: Cream
Beauty Purpose: Moisturizing
Recommended Skin Type: Dry, Sensitive
Net weight: 10 fl oz (US)
TCIN: 94736815
UPC: 810129110609
Item Number (DPCI): 037-14-9157
Origin: Made in the USA
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

colloidal oatmeal' '1.0%

Purpose

Skin Protectant

Uses

Uses Temporarily protects and helps relieve minor skin irritation and itching due to: rashes, poison ivy, oak, or sumac, eczema, insect bites

Directions

Directions Apply as needed.

Other information

Other Information Store in controlled temperatures (4-20°C/39-68°F). Keep in a dark and dry place.

Inactive ingredients

water (aqua), carthamus tinctorius seed oil, cetyl alcohol, glycerin, butyrospermum parkii butter, caprylic/capric triglyceride, dimethicone, c10-18 triglycerides, allantoin, adenosine, cetearyl olivate, sorbitan olivate, ceramide ap, ceramide eos, ceramide eop, ceramide np, ceramide ns, cholesterol, caprooyl phytosphingosine, caprooyl sphingosine, glycolipids, phospholipids, sodium stearoyl glutamate, beheric acid, ceteareth-25, glycine soja oil, glycine soja sterols, ascorbyl palmitate, tocopherol, lecithin, glyceryl stearate, glyceryl oleate, carbomer, caprylyl glycol, hydroxyacetophenone, phenoxyethanol, ethylhexylglycerin, 1,2-hexanediol, tocopheryl acetate, tetrasodium glutamate diacetate, sodium chloride, sodium hydroxide, citric acid.

Shipping details

Estimated ship dimensions: 1.85 inches length x 2.44 inches width x 8.94 inches height
Estimated ship weight: 0.705 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: Can this be used on your lower lady bits

submitted by Dolly - 21 days ago
  • A: Our Barrier Therapy Skin Protectant Cream has been formulated for external use only.

    submitted byPrequel - 15 days ago
    Brand expert

Q: Is this safe to use on babies skin?

submitted by Kris - 1 month ago
  • A: Our formulations are formulated to be safe and gentle on sensitive skin. We have not tested them on babies or infants at this point. We always advise you check with your pediatrician.

    submitted byPrequel - 1 month ago
    Brand expert

Q: What skin issues does the cream help alleviate?

submitted by AI Shopping Assistant - 1 month ago
  • A: The cream alleviates itchiness and minor irritation due to dry skin and eczema.

    submitted byAI Shopping Assistant - 1 month ago
    Ai generated

Q: Can this cream be used on sensitive skin?

submitted by AI Shopping Assistant - 1 month ago
  • A: Yes, it is safe for sensitive skin and eczema-prone skin.

    submitted byAI Shopping Assistant - 1 month ago
    Ai generated

Q: Is this cream greasy or fragrance-free?

submitted by AI Shopping Assistant - 1 month ago
  • A: The cream is non-greasy and fragrance-free, making it suitable for everyday use.

    submitted byAI Shopping Assistant - 1 month ago
    Ai generated

Q: What key ingredients are in this skin protectant?

submitted by AI Shopping Assistant - 1 month ago
  • A: It contains colloidal oatmeal, multi-ceramide blend, allantoin, and adenosine.

    submitted byAI Shopping Assistant - 1 month ago
    Ai generated

Q: What is the primary purpose of this skincare product?

submitted by AI Shopping Assistant - 1 month ago
  • A: This product is designed for moisturizing and protecting dry, distressed skin.

    submitted byAI Shopping Assistant - 1 month ago
    Ai generated

Q: Does this have dimethicone in it?

submitted by Lizzydrew22 - 2 months ago
  • A: Yes, Barrier Therapy does contain dimethicone in it.

    submitted byPrequel - 2 months ago
    Brand expert

Q: Is this product gluten free?

submitted by tayhungerford - 3 months ago
  • A: Yes, our Barrier Therapy Cream is gluten-free.

    submitted byPrequel - 3 months ago
    Brand expert

Q: can you use if you have dry cracked skin

submitted by M - 3 months ago
  • A: Yes, you can use our Barrier Therapy on irritated, dry or cracked skin, so long as it is not an open wound. In that case, we'd recommend checking with your doctor.

    submitted byPrequel - 3 months ago
    Brand expert

Additional product information and recommendations

4.0 out of 5 stars with 37 reviews
effectiveness: 3.76 out of 5
quality: 3.82 out of 5
value: 3.88 out of 5
66% would recommend
18 recommendations
5 out of 5 stars
25 March, 2026Verified purchase

(no review title)

My favorite face and body moisturizer.
Hamna
Did you find this review helpful?
3 out of 5 stars
24 March, 2026Verified purchase

(no review title)

It did the job with keeping moisture and calming my skin especially with my angry eczema, but i started to form red spots all over my face 🥲
Elisa
effectiveness: 3 out of 5
quality: 2 out of 5
value: 2 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
22 March, 2026Verified purchase

(no review title)

Just tried for a few days and this has stopped my eczema itchiness! My skin loves this! Smell is very subtle too. Thank you! Love!!
Sarah
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
2 out of 5 stars
Thumbs down graphic, would not recommend
19 March, 2026Verified purchase

Might just be me

I think I’m one of the few people that found this cream irritating. At first I didn’t notice it but the more I’ve used it the more my skin does not like it. On my body it does okay but it leaves a slight burning feeling on my face compared to other similar creams (ex CerAve, Aveeno, Uriage). I tend to really go for products that cater to barrier protection especially for winter and was so excited to try it but 2 months out and I think it’s just not for me. Please spot test this before using!
Kant
effectiveness: 2 out of 5
quality: 4 out of 5
value: 4 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
14 March, 2026Verified purchase

GOLD

This lotion does it all. It’s phenomenal as a face and body moisturizer, and I’m saying that as someone with acne prone skin. I don’t quite get the negative reviews. My experience has been amazing!
mCO
3 guests found this review helpful. Did you?
2 out of 5 stars
7 March, 2026Verified purchase

Good as a body lotion but...

I have very sensitive skin on my face and this made my skin turn very red and itchy. It works well for my body, just not my face, unfortunately.
Mick
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
27 February, 2026

Buy it!

Phenomenal! Not greasy and hydrates like no other lotion. I’ve been using it for my hands and love it!
my reviews
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
1 out of 5 stars
24 February, 2026Verified purchase

Not for Eczema prone skin

Did not help my daughter’s skin with eczema.
Brittany
1 guest found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
23 February, 2026Verified purchase

Just beware!

I bought this thinking it will work because I seen so many ads that this was great for Eczema prone skin! So I bought 2 for my older daughter who had this skin problem since she was little but has been maintaining it with making sure she puts her anti itch creams and moisturizing lotions on her. But once she put this on her face it stared to become hot and itchy she she had to rinse it off right away!! And the 2 one was for my youngest son who also has Eczema but wasn't severe as his sister's. But has used it twice and he started to have a itchy rash all over his body!!! And I started to have a rash on my hands and itchy body when I don't even have eczema smh!!!! Had to throw both away!!! I think it was the colloidal oatmeal ingredient that was effecting this rash! Because the other lotions and creams we have been using doesn't have this ingredient in them! So just beware if you have a allergic reaction to oatmeal don't get this!!
SVue
effectiveness: 1 out of 5
quality: 1 out of 5
value: 1 out of 5
Did you find this review helpful?
3 out of 5 stars
20 February, 2026Verified purchase

(no review title)

Don’t use this on your face/areas that are acne prone. This has a lot of comedogenic ingredients that will clog your pores and cause acne over time. The product is fine but there’s better out there but for a higher price. You get a good price per ounce with this product.
Emily
2 guests found this review helpful. Did you?
2 out of 5 stars
Thumbs down graphic, would not recommend
17 February, 2026Verified purchase

(no review title)

Be careful using it on your face - I don't have sensitive skin and it made me break out on my forehead with small red acne and made my face feel tight, felt like it didn't help with face barrier repair and clogged the face instead. I've been using it on my body and it's been fine, but it's not too moisturizing because of the thin consistency. Definitely a skip.
A
effectiveness: 1 out of 5
quality: 1 out of 5
value: 3 out of 5
Did you find this review helpful?
5 out of 5 stars
17 February, 2026Verified purchase

(no review title)

incredible moisturizer. dermatologist owned brand. quantity makes it easy to slather everywhere. TYSM
Karlee
1 guest found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
16 February, 2026Verified purchase

(no review title)

This did not work for my child with eczema.
Gabi
effectiveness: 1 out of 5
quality: 1 out of 5
value: 1 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
14 February, 2026Verified purchase

Great for Wind-Chapped Skin

I love Prequel, but I especially love this moisturizer. I use it on my face and body, and I feel like it’s perfect for both cases. The fact that it has ceramides and colloidal oatmeal makes it a really good fit for my dry, sensitive, and Midwest-winter wind-chapped face.
M
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
8 February, 2026Verified purchase

GREAT BUY

Highly recommend this cream. Great value and superb ingredients. Cant ask for more. I wish Target had the full Prequel line!
TargetLover24
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
2 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
7 February, 2026

perfect for barista hands

If you're a barista and are struggling with dry hands from the sanitizer, I highly recommend this! It lasts through multiple hand washes.
tia
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
30 January, 2026

(no review title)

I was suffering from excruciatingly, painful and itchy, cracked oozing eczema on my hands and I have tried everything Under The Sun ☀️. This is so far working amazing. It took the itch and pain away within an hour and it keeps looking better. I use this then lock it in with Cerave healing ointment on top.
Domenique
2 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
28 January, 2026

My new favorite!

I suffer from dry skin, and during the cold winter months in the Midwest, my hands can at times become unbearable. I have tried every lotion and hand cream you can think of, and this product has instantly become my new favorite. With one application, I could instantly feel the difference in my skin. Throw out your old hand cream, and run to Target and pick this up. You won’t be disappointed!
Brendan
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
26 January, 2026Verified purchase

It's a no for me

The texture is odd and, as others have said, it pills like crazy over and under other products which is not practical for use. It’s also not moisturizing enough to sooth my skin in the winter.
Mel
4 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
21 January, 2026Verified purchase

Good hand cream/night cream

I use this as a hand cream after I moisturize my body, do my routine skin care, on my elbows, and before bed as my hand cream (and in between if needed). I don’t know why people are worried about the smell. It is unscented and the smell you may be smelling is the compounded mixture of ingredients. It’s a great cream but I do not know how it works as a face cream or body cream. It works well on hands and needs a little bit to soak in but not too long. Really liking the Prequel brand!
furbabymom
effectiveness: 5 out of 5
quality: 5 out of 5
value: 3 out of 5
5 guests found this review helpful. Did you?

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